siRNA, Anti-TNFRSF12A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76879WQ-2OMe)

The product SIRGT76879WQ-2OMe is a type of small interfering RNA (siRNA) that targets TNFRSF12A gene and regulates the expression of gene. The siRNA interferes with the expression of TNFRSF12A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016639.2
Alternative Names CD266; FN14; TWEAKR
Related Diseases Alcoholic Hepatitis
Purification HPLC
Target Gene
Gene ID 51330
Uniprot ID Q9NP84
Sub Cat Target Species Modification Scale  
SIRGT77879WQ-2F TNFRSF12A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78879WQ-2MOE TNFRSF12A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79879WQ-LNA TNFRSF12A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76879WQ-RB TNFRSF12A Human Ribo-modified Inquiry
SIRGT77879WQ-BB TNFRSF12A Human Backbone-modified Inquiry

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