siRNA, Anti-USP45, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT51191WQ-2OMe)

The product SIRGT51191WQ-2OMe is a type of small interfering RNA (siRNA) that targets USP45 gene and regulates the expression of gene. The siRNA interferes with the expression of USP45 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001080481.1
Related Diseases Leber Congenital Amaurosis 19
Purification HPLC
Target Gene
Gene ID 85015
Uniprot ID Q70EL2
Sub Cat Target Species Modification Scale  
SIRGT52191WQ-2F USP45 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53191WQ-2MOE USP45 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT51191WQ-RB USP45 Human Ribo-modified Inquiry

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