siRNA, Anti-USP45, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT51191WQ-2OMe)
The product SIRGT51191WQ-2OMe is a type of small interfering RNA (siRNA) that targets USP45 gene and regulates the expression of gene. The siRNA interferes with the expression of USP45 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001080481.1 |
| Related Diseases | Leber Congenital Amaurosis 19 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT52191WQ-2F | USP45 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT53191WQ-2MOE | USP45 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT51191WQ-RB | USP45 | Human | Ribo-modified |