siRNA, Anti-ZNRF4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56707WQ-2OMe)

The product SIRGT56707WQ-2OMe is a type of small interfering RNA (siRNA) that targets ZNRF4 gene and regulates the expression of gene. The siRNA interferes with the expression of ZNRF4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_181710.3
Alternative Names RNF204; SPERIZIN; Ssrzf1; spzn
Related Diseases Deafness
Purification HPLC
Target Gene
Gene ID 148066
Uniprot ID Q8WWF5
Sub Cat Target Species Modification Scale  
SIRGT57707WQ-2F ZNRF4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58707WQ-2MOE ZNRF4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59707WQ-LNA ZNRF4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56707WQ-RB ZNRF4 Human Ribo-modified Inquiry
SIRGT57707WQ-BB ZNRF4 Human Backbone-modified Inquiry

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