siRNA, Anti-AAMP, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01007WQ-2OMe)
The product SIRGT01007WQ-2OMe is a type of small interfering RNA (siRNA) that targets AAMP gene and regulates the expression of gene. The siRNA interferes with the expression of AAMP genes with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001087.4; NM_001302545.1 |
| Related Diseases | Non-small cell lung cancer |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT02007WQ-2F | AAMP | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT03007WQ-2MOE | AAMP | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT97022WQ-2F | Aamp | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT98022WQ-2MOE | Aamp | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT01007WQ-RB | AAMP | Human | Ribo-modified | ||
| SIRGT96022WQ-RB | Aamp | Mouse | Ribo-modified | ||
| SIRGT02007WQ-BB | AAMP | Human | Backbone-modified |
