siRNA, Anti-Human ABCB7, LNA(CAT#: SIRGT04014WQ-LNA)

The product SIRGT04014WQ-LNA is a type of small interfering RNA (siRNA) that targets ABCB7 gene and regulates the expression of gene. The siRNA interferes with the expression of ABCB7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001271696.2; NM_001271697.2; NM_001271698.2; NM_001271699.2; NM_004299.5
Alternative Names ABC7; ASAT; Atm1p; EST140535
Related Diseases Mitochondrial iron accumulation, Isodicentric (X)(q13), Sideroblastic anemia
Purification HPLC
Target Gene
Gene ID 22
Uniprot ID O75027

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