siRNA, Anti-ARG1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01260WQ-2OMe)

The product SIRGT01260WQ-2OMe is a type of small interfering RNA (siRNA) that targets ARG1 gene and regulates the expression of gene. The siRNA interferes with the expression of ARG1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000045.3; NM_001244438.1
Related Diseases Argininemia, Intestinal Schistosomiasis
Purification HPLC
Target Gene
Gene ID 383
Uniprot ID P05089
Sub Cat Target Species Modification Scale  
SIRGT02260WQ-2F ARG1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03260WQ-2MOE ARG1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04260WQ-LNA ARG1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01260WQ-RB ARG1 Human Ribo-modified Inquiry
SIRGT02260WQ-BB ARG1 Human Backbone-modified Inquiry

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