siRNA, Anti-ATP6V1B2, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT01349WQ-2OMe)

The product SIRGT01349WQ-2OMe is a type of small interfering RNA (siRNA) that targets ATP6V1B2 gene and regulates the expression of gene. The siRNA interferes with the expression of ATP6V1B2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001693.3
Alternative Names ATP6B1B2; ATP6B2; DOOD; HO57; VATB; VPP3; Vma2; ZLS2
Related Diseases Deafness, Zimmermann-Laband Syndrome
Purification HPLC
Target Gene
Gene ID 526
Uniprot ID P21281
Sub Cat Target Species Modification Scale  
SIRGT04349WQ-LNA ATP6V1B2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01349WQ-RB ATP6V1B2 Human Ribo-modified Inquiry
SIRGT02349WQ-BB ATP6V1B2 Human Backbone-modified Inquiry

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