siRNA, Anti-ATP7A, LNA-modified(CAT#: SIRGT04356WQ-LNA)

The product SIRGT04356WQ-LNA is a type of small interfering RNA (siRNA) that targets ATP7A gene and regulates the expression of gene. The siRNA interferes with the expression of ATP7A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000052.6; NM_001282224.1
Alternative Names DSMAX; MK; MNK; SMAX3
Related Diseases Menkes disease, X-linked distal spinal muscular atrophy, Occipital horn syndrome
Purification HPLC
Target Gene
Gene ID 538
Uniprot ID Q04656

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