siRNA, Anti-ATP8B1, LNA-modified(CAT#: SIRGT19322WQ-LNA)

The product SIRGT19322WQ-LNA is a type of small interfering RNA (siRNA) that targets ATP8B1 gene and regulates the expression of gene. The siRNA interferes with the expression of ATP8B1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_005603.5
Alternative Names ATPIC; BRIC; FIC1; ICP1; PFIC; PFIC1
Related Diseases Cholestasis, Progressive Familial Intrahepatic
Purification HPLC
Target Gene
Gene ID 5205
Uniprot ID O43520

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