siRNA, Anti-CENPB, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01738WQ-2OMe)

The product SIRGT01738WQ-2OMe is a type of small interfering RNA (siRNA) that targets CENPB gene and regulates the expression of gene. The siRNA interferes with the expression of CENPB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001810.5
Related Diseases Crest Syndrome, Raynaud Disease
Purification HPLC
Target Gene
Gene ID 1059
Uniprot ID P07199
Sub Cat Target Species Modification Scale  
SIRGT02738WQ-2F CENPB Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03738WQ-2MOE CENPB Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04738WQ-LNA CENPB Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01738WQ-RB CENPB Human Ribo-modified Inquiry
SIRGT02738WQ-BB CENPB Human Backbone-modified Inquiry

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