siRNA, Anti-CHRM4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01782WQ-2OMe)

The product SIRGT01782WQ-2OMe is a type of small interfering RNA (siRNA) that targets CHRM4 gene and regulates the expression of gene. The siRNA interferes with the expression of CHRM4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000741.3
Alternative Names HM4; M4R
Related Diseases Ureterolithiasis, Cone-Rod Dystrophy
Purification HPLC
Target Gene
Gene ID 1132
Uniprot ID P08173
Sub Cat Target Species Modification Scale  
SIRGT02782WQ-2F CHRM4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03782WQ-2MOE CHRM4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04782WQ-LNA CHRM4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01782WQ-RB CHRM4 Human Ribo-modified Inquiry
SIRGT02782WQ-BB CHRM4 Human Backbone-modified Inquiry

Related Products