siRNA, Anti-CR1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01933WQ-2OMe)

The product SIRGT01933WQ-2OMe is a type of small interfering RNA (siRNA) that targets CR1 gene and regulates the expression of gene. The siRNA interferes with the expression of CR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000573.3; NM_000651.4
Alternative Names C3BR; C4BR; CD35; KN
Related Diseases Malaria
Purification HPLC
Target Gene
Gene ID 1378
Uniprot ID P17927
Sub Cat Target Species Modification Scale  
SIRGT02933WQ-2F CR1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03933WQ-2MOE CR1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04933WQ-LNA CR1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01933WQ-RB CR1 Human Ribo-modified Inquiry
SIRGT02933WQ-BB CR1 Human Backbone-modified Inquiry

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