siRNA, Anti-CTNNB1, 2'-OMe-modified(CAT#: SIRGT06019WQ-2OMe)

The product SIRGT06019WQ-2OMe is a type of small interfering RNA (siRNA) that targets CTNNB1 gene and regulates the expression of gene. The siRNA interferes with the expression of CTNNB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-O-methyl (2'-OMe)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001098209.1; NM_001098210.1; NM_001330729.1; NM_001904.3
Alternative Names CTNNB; EVR7; MRD19; armadillo
Related Diseases Colorectal cancer (CRC), Pilomatrixoma (PTR), Medulloblastoma (MDB), Ovarian cancer
Purification HPLC
Target Gene
Gene ID 1499
Uniprot ID P35222

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