siRNA, Anti-CTNNB1, LNA-modified(CAT#: SIRGT09019WQ-LNA)

The product SIRGT09019WQ-LNA is a type of small interfering RNA (siRNA) that targets CTNNB1 gene and regulates the expression of gene. The siRNA interferes with the expression of CTNNB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001098209.1; NM_001098210.1; NM_001330729.1; NM_001904.3
Alternative Names CTNNB; EVR7; MRD19; armadillo
Related Diseases Colorectal cancer (CRC), Pilomatrixoma (PTR), Medulloblastoma (MDB), Ovarian cancer
Purification HPLC
Target Gene
Gene ID 1499
Uniprot ID P35222

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