siRNA, Anti-EPHA8, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06374WQ-2OMe)

The product SIRGT06374WQ-2OMe is a type of small interfering RNA (siRNA) that targets EPHA8 gene and regulates the expression of gene. The siRNA interferes with the expression of EPHA8 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001006943.2; NM_020526.4
Alternative Names EEK; EK3; HEK3
Related Diseases ERK Signaling
Purification HPLC
Target Gene
Gene ID 2046
Uniprot ID P29322
Sub Cat Target Species Modification Scale  
SIRGT07374WQ-2F EPHA8 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08374WQ-2MOE EPHA8 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09374WQ-LNA EPHA8 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06374WQ-RB EPHA8 Human Ribo-modified Inquiry
SIRGT07374WQ-BB EPHA8 Human Backbone-modified Inquiry

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