siRNA, Anti-GUCA1C, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31154WQ-2OMe)

The product SIRGT31154WQ-2OMe is a type of small interfering RNA (siRNA) that targets GUCA1C gene and regulates the expression of gene. The siRNA interferes with the expression of GUCA1C gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005459.3
Alternative Names GCAP3
Related Diseases Leber Congenital Amaurosis 1
Purification HPLC
Target Gene
Gene ID 9626
Uniprot ID O95843
Sub Cat Target Species Modification Scale  
SIRGT32154WQ-2F GUCA1C Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33154WQ-2MOE GUCA1C Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34154WQ-LNA GUCA1C Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31154WQ-RB GUCA1C Human Ribo-modified Inquiry
SIRGT32154WQ-BB GUCA1C Human Backbone-modified Inquiry

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