siRNA, Anti-ITGAE, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11375WQ-2OMe)

The product SIRGT11375WQ-2OMe is a type of small interfering RNA (siRNA) that targets ITGAE gene and regulates the expression of gene. The siRNA interferes with the expression of ITGAE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002208.4
Alternative Names CD103; HUMINAE
Related Diseases Hairy Cell Leukemia, Splenic Marginal Zone Lymphoma
Purification HPLC
Target Gene
Gene ID 3682
Uniprot ID P38570
Sub Cat Target Species Modification Scale  
SIRGT12375WQ-2F ITGAE Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13375WQ-2MOE ITGAE Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14375WQ-LNA ITGAE Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11375WQ-RB ITGAE Human Ribo-modified Inquiry
SIRGT12375WQ-BB ITGAE Human Backbone-modified Inquiry

Related Products