siRNA, Anti-LTA4H, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11624WQ-2OMe)

The product SIRGT11624WQ-2OMe is a type of small interfering RNA (siRNA) that targets LTA4H gene and regulates the expression of gene. The siRNA interferes with the expression of LTA4H gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000895.2; NM_001256643.1; NM_001256644.1
Related Diseases Chronic obstructive pulmonary disease (COPD)
Purification HPLC
Target Gene
Gene ID 4048
Uniprot ID P09960
Sub Cat Target Species Modification Scale  
SIRGT12624WQ-2F LTA4H Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13624WQ-2MOE LTA4H Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14624WQ-LNA LTA4H Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11624WQ-RB LTA4H Human Ribo-modified Inquiry
SIRGT12624WQ-BB LTA4H Human Backbone-modified Inquiry

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