siRNA, Anti-NSUN2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41362WQ-2OMe)

The product SIRGT41362WQ-2OMe is a type of small interfering RNA (siRNA) that targets NSUN2 gene and regulates the expression of gene. The siRNA interferes with the expression of NSUN2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001193455.1
Alternative Names MISU; MRT5; SAKI; TRM4
Related Diseases Dubowitz Syndrome
Purification HPLC
Target Gene
Gene ID 54888
Uniprot ID Q08J23
Sub Cat Target Species Modification Scale  
SIRGT42362WQ-2F NSUN2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43362WQ-2MOE NSUN2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44362WQ-LNA NSUN2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41362WQ-RB NSUN2 Human Ribo-modified Inquiry
SIRGT42362WQ-BB NSUN2 Human Backbone-modified Inquiry

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