siRNA, Anti-PKIA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16579WQ-2OMe)

The product SIRGT16579WQ-2OMe is a type of small interfering RNA (siRNA) that targets PKIA gene and regulates the expression of gene. The siRNA interferes with the expression of PKIA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006823.3; NM_181839.2
Alternative Names PRKACN1
Related Diseases Myometrial Relaxation and Contraction Pathways
Purification HPLC
Target Gene
Gene ID 5569
Uniprot ID P61925
Sub Cat Target Species Modification Scale  
SIRGT17579WQ-2F PKIA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18579WQ-2MOE PKIA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19579WQ-LNA PKIA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16579WQ-RB PKIA Human Ribo-modified Inquiry
SIRGT17579WQ-BB PKIA Human Backbone-modified Inquiry

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