siRNA, Anti-SERPINA3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01005WQ-2OMe)

The product SIRGT01005WQ-2OMe is a type of small interfering RNA (siRNA) that targets SERPINA3 gene and regulates the expression of gene. The siRNA interferes with the expression of SERPINA3 genes with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001085.4
Alternative Names ACT; AACT; GIG24; GIG25
Related Diseases Parkinson disease, Chronic obstructive pulmonary disease
Purification HPLC
Target Gene
Gene ID 12
Uniprot ID P01011
Sub Cat Target Species Modification Scale  
SIRGT02005WQ-2F SERPINA3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03005WQ-2MOE SERPINA3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04005WQ-LNA SERPINA3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01005WQ-RB SERPINA3 Human Ribo-modified Inquiry
SIRGT02005WQ-BB SERPINA3 Human Backbone-modified Inquiry

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