siRNA, Anti-U2SURP, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36885WQ-2OMe)

The product SIRGT36885WQ-2OMe is a type of small interfering RNA (siRNA) that targets U2SURP gene and regulates the expression of gene. The siRNA interferes with the expression of U2SURP gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001080415.1
Alternative Names SR140; fSAPa
Related Diseases Retinitis Pigmentosa
Purification HPLC
Target Gene
Gene ID 23350
Uniprot ID O15042
Sub Cat Target Species Modification Scale  
SIRGT37885WQ-2F U2SURP Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38885WQ-2MOE U2SURP Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39885WQ-LNA U2SURP Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36885WQ-RB U2SURP Human Ribo-modified Inquiry
SIRGT37885WQ-BB U2SURP Human Backbone-modified Inquiry

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