siRNA, Anti-VAMP2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21489WQ-2OMe)

The product SIRGT21489WQ-2OMe is a type of small interfering RNA (siRNA) that targets VAMP2 gene and regulates the expression of gene. The siRNA interferes with the expression of VAMP2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001330125.1; NM_014232.2
Alternative Names SYB2; VAMP-2
Related Diseases Neurodevelopmental Disorder
Purification HPLC
Target Gene
Gene ID 6844
Uniprot ID P63027
Sub Cat Target Species Modification Scale  
SIRGT22489WQ-2F VAMP2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23489WQ-2MOE VAMP2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24489WQ-LNA VAMP2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21489WQ-RB VAMP2 Human Ribo-modified Inquiry
SIRGT22489WQ-BB VAMP2 Human Backbone-modified Inquiry

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