Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Glucagon like peptide 1 receptor |
| Gene Name | GLP1R |
| Uniprot | P43220 (Human); O35659 (Mouse) |
| Synonym | GLP-1; GLP-1R; GLP-1-R; GLP-1 receptor; GLP1 receptor; seven transmembrane helix receptor |
| Background | The glucagon-like peptide 1 receptor (GLP1R) is a receptor protein encoded by gene GLP1R. GLP1R consists of two domains, an extracellular (ECD) that binds the C-terminal helix of GLP-1, and a transmembrane (TMD) domain that binds the N-terminal region of GLP-1. It was found on beta cells of the pancreas and involved in the control of blood sugar level by enhancing insulin secretion. It also stimulates glucose-induced insulin secretion. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX449 | NativeExtract™ Human GLP1R Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3575K | MemDX™ Membrane Protein Human GLP1R (Glucagon like peptide 1 receptor) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| MPVLP-017 | MemDX™ Recombinant Human GLP1R Membrane Protein in Virus-Like Particles (MP-VLPs) | HEK293 cells | Full length | VLPs |
| MPX4616K | MemDX™ Membrane Protein Human GLP1R Expressed in Mammalian cell expression system, Partial (24-145aa) | Mammalian cell | Partial | N/A |
| MPX4239K | MemDX™ Membrane Protein Human GLP1R Expressed in E.coli, Partial (24-145aa) | E.coli | Partial | N/A |
| Please for more products or customization | ||||
With our advanced cell line construction platform and extensive experience, we offer you high-quality and highly stable membrane protein stable cell lines to support your research and drug development.
| CAT# | Product Name | Target Species | Host Cell |
| S01YF-0324-KX140 | MemDX™ Human GLP1R BHK Cell Line | Human | HEK293T |
| S01YF-1022-KX359 | MemDX™ Human FLAG tagged GLP1R HEK293T Cell Line, Calcium flux assay | Human | HEK293T |
| Please contact us for more products or customization | |||
Q***n: NativeExtract™ Human GLP1R Membrane Protein (Full length, Super Nanodisc)
I recently purchased the GLP1R protein from Creative Biolabs for my research, and I am extremely impressed with its performance. The protein worked exceptionally well in ELISA assays, showing high sensitivity and specificity.
17/ Aug/2023
A***y: The technical support team was also very helpful, providing detailed guidance on assay optimization. I highly recommend this product!
03/ Oct/2023
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers targeted production services. Use tissue-specific promoters to direct the production of GLP-1 in specific tissues like the liver, muscle, islet, and gut. This targeted approach may improve therapeutic efficacy by mimicking the natural secretion pattern of GLP-1 and reducing the need for frequent injections.
Creative Biolabs offers vector development services. Develop viral vectors to deliver the GLP-1 gene. Viral vectors can efficiently transfer the gene into target cells, but challenges such as immune response and potential for insertional mutagenesis need to be addressed. Explore non-viral gene delivery methods, which generally have lower immunogenicity and are easier to produce. However, they may have lower transfection efficiency compared to viral vectors.
Creative Biolabs offers comprehensive and innovative services to drive the development of GLP1R cell therapy. Please for more services.
Creative Biolabs offers cell functional enhancement services. Strategies to augment cellular responses mediated by the Glucagon-like peptide-1 receptor (GLP1R) can involve intrinsic modifications to the receptor protein itself. Such molecular engineering approaches might aim to enhance key functional parameters. Achieving these modifications often relies on established protein engineering techniques; these include targeted site-directed mutagenesis for introducing precise amino acid substitutions or, alternatively, the design and implementation of chimeric receptor constructs, which strategically fuse domains from disparate receptors to potentially combine advantageous functional properties.
Creative Biolabs offers delivery methods development services. For the deployment of engineered cellular therapeutics, distinct administration strategies are considered. One primary modality involves direct, localized delivery into the intended target tissue. The rationale underpinning this approach is the establishment of a high concentration of the therapeutic cell population specifically at the site of desired activity. Alternatively, systemic infusion routes, including intravenous or intraperitoneal administration, offer a different paradigm for cell delivery. This methodology inherently relies upon the administered cells possessing the requisite biological machinery to home effectively towards the designated tissue or organ.
Creative Biolabs offers cell tracking technologies development services. To elucidate cellular behavior in vivo, we employ various tracking methodologies. One prominent technique involves the labelling of target cells with magnetic nanoparticles. These nanoparticles serve as contrast agents detectable via Magnetic Resonance Imaging (MRI), a powerful modality that consequently permits the non-invasive, longitudinal assessment of the cells' spatiotemporal distribution within the host organism over extended periods. Alternatively, genetic modification strategies offer another avenue for cellular surveillance. This approach facilitates the monitoring of not only cell location but also provides insights into cellular viability and, potentially, functional status within the complex milieu of a live animal model. Such reporter systems are invaluable tools for dynamic biological investigation.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
