1,2-Distearoyl-sn-glycero-3-phosphoethanolamine

DSPE (1,2-Distearoyl-sn-glycero-3-phosphoethanolamine) is a saturated, zwitterionic phospholipid belonging to the phosphatidylethanolamine (PE) class, featuring two C18:0 stearic acid acyl chains. PE is synthesized mainly from CDP-ethanolamine and diacylglycerol, playing a role as a core component of cellular membranes. DSPE is a key component in advanced lipid-based drug and gene delivery systems, where it is often conjugated with polyethylene glycol (PEG) to create "stealth" liposomes with extended circulation times.

1069-79-0

DSPE (18:0/18:0 PE); PE(18:0/18:0); [(2R)-3-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate; 2-Azaniumylethyl ((2R)-2,3-di(octadecanoyloxy)propyl) phosphate; Distearoyl phosphatidylethanolamine

C₄₁H₈₂NO₈P

748.1

MFCD00036777

InChI=1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1

LVNGJLRDBYCPGB-LDLOPFEMSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.