1-Pentadecanoyl-sn-glycero-3-phosphocholine

This compound, 15:0 LysoPC (Lysophosphatidylcholine), is a mono-acyl glycerophospholipid produced in vivo primarily through the hydrolysis of the sn-2 acyl chain of Phosphatidylcholine (PC) by Phospholipase A2 (PLA2). LysoPC is a significant lipid component of oxidized low-density lipoprotein (Ox-LDL) and is implicated as a bioactive pro-inflammatory lipid. It plays an important role in the pathogenesis of inflammatory diseases and atherosclerosis by altering various functions in vascular cells. LysoPC also serves as a critical substrate for the lysophospholipase activity of Autotaxin/LysoPLD, which generates lysophosphatidic acid, another potent signaling molecule central to cell motility.

108273-89-8

1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; [(2R)-2-Hydroxy-3-pentadecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate; 15:0 LysoPC; LysoPC(15:0); LPC(15:0/0:0); Lysophosphatidylcholine(15:0); LyPC(15:0)

C₂₃H₄₈NO₇P

481.6

MFCD00674356

InChI=1S/C23H48NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23(26)29-20-22(25)21-31-32(27,28)30-19-18-24(2,3)4/h22,25H,5-21H2,1-4H3/t22-/m1/s1

RJZVWDTYEWCUAR-JOCHJYFZSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.