3S-PI(3,4,5)P3 diC16

A highly stable synthetic derivative of the critical second messenger PI(3,4,5)P3. The introduction of the sulfur atom at the 3-position renders the molecule resistant to hydrolysis by lipid phosphatases like PTEN, making it an invaluable tool for sustained in vitro studies of PI 3-kinase downstream signaling events and effector binding kinetics.

3S-PtdIns(3,4,5)P3, diC16; PtdIns(3,4,5)P3 3-phosphothioate

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.