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A synthetic, biotin-labeled analog of D-myo-Inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4), a higher-order inositol polyphosphate. Ins(1,3,4,5)P4 plays significant roles in regulating calcium entry, endosomal transport, and acting as a precursor in the metabolic cascade leading to Inositol hexakisphosphate (InsP6). The incorporation of a biotin tag allows for efficient affinity-based studies to delineate its receptor targets and enzymatic processing.