Biotin PI(3,4,5)P3

This is a biotin-labeled version of phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 is generated from PIP2 by the catalytic activity of class I phosphoinositide 3-kinases (PI3Ks) and is a key second messenger that dictates cell fate. It is a master regulator of cell survival, proliferation, and metabolism, largely by recruiting and activating signaling proteins such as AKT. Its levels are strictly counter-regulated by phosphatases, like the tumor suppressor PTEN.

Biotin phosphatidylinositol 3,4,5-trisphosphate; Biotin-PIP3; Biotinylated PI(3,4,5)P3

C₃₇H₆₁N₄Na₇O₂₅P₄S

1,278.78

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.