Cationic lipid CAP2

CAP2 is a cationic lipid utilized to create LNPs for plasmid DNA delivery, enabling transient, long-lasting gene expression in vivo. LNPs formulated with CAP2 and reporter plasmid DNA demonstrated successful transfection in the knockout mouse model, maintaining protein expression for an extended period after a single intramuscular injection, making it a promising tool for gene replacement therapies.

2943226-53-5

Bis((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-
2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl) (3-(dimethylamino)propyl) phosphate; Cholesterol-amino-phosphate CAP2

C₅₉H₁₀₂NO₄P

920.44

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.