Glycerophosphoinositol 4-phosphate

Glycerophosphoinositol 4-phosphate (GroPI(4)P) is a water-soluble, diffusable metabolite of the phosphoinositide signaling pathway. It is formed by the de-acylation of Phosphatidylinositol 4-phosphate (PI(4)P). PI(4)P is the primary precursor for phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and plays fundamental roles in regulating sphingomyelin and glycosphingolipid metabolism as well as membrane trafficking at the exit point of the Golgi complex. GroPI(4)P itself has emerged as a bioactive lipid that modulates the actin cytoskeleton and is implicated in the regulation of Rho GTPases and T-cell signaling.

129830-96-2

GroPI(4)P; GroPIP; (1R,2R,3R,4R,5R,6S)-4-((((R)-2,3-Dihydroxypropoxy)(hydroxy)phosphoryl)oxy)-2,3,5,6-tetrahydroxycyclohexyl dihydrogen phosphate

C₉H₁₇Na₃O₁₄P₂

480.1

InChI=1S/C9H20O14P2/c10-1-3(11)2-21-25(19,20)23-9-6(14)4(12)8(5(13)7(9)15)22-24(16,17)18/h3-15H,1-2H2,(H,19,20)(H2,16,17,18)/t3-,4-,5+,6-,7-,8?,9?/m1/s1

MRHAWIJFXZJZEV-LLGVDSJGSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.