GlycoErase™ AMY1B Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF381)

Description	GlycoErase™ AMY1B knockout HEK293 cell line is a human embryonic kidney (HEK293) model in which AMY1B expression has been deleted. AMY1B encodes a salivary amylase isoenzyme contributing to starch and glycogen degradation. The loss of AMY1B expression in the HEK293 system provides a human-based platform to examine alpha-amylase isoform diversity, functional regulation of carbohydrate digestion, and metabolic adaptation, supporting applications in enzymology, human metabolism studies, and therapeutic enzyme engineering.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	AMY1B
Full Name	Amylase Alpha 1B
Alternative Name	AMY1
Location	1p21.1
Gene ID	277
Summary	This salivary gland amylase isoenzyme hydrolyzes 1,4-alpha-glucoside bonds in carbohydrates, catalyzing the first step of starch and glycogen digestion. It belongs to a gene cluster highly expressed in salivary glands or pancreas.