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GlycoErase™ B4GALT2 Knockout Human Lung Cancer Cell A-427

CAT#: GLJF-0525-JF1402

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Overview Specification Target Information Related Products
Overview
Description
The B4GALT2 knockout A-427 cell line, deficient in beta-1,4-galactosyltransferase 2 with diverse glycosylation functions, enables the study of glycoconjugate biosynthesis disruption in lung adenocarcinoma, potentially affecting various beta-1,4-galactosyltransferase dependent glycosylation pathways and revealing functional redundancy or specificity within the beta4GalT family in tumors.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:3
Cell Line
A-427
Primary Disease
Non-Small Cell Lung Cancer
Lineage
Lung
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
B4GALT2
Compounds Targeting
N-acetyl-D-glucosamine
Full Name
Beta-1,4-galactosyltransferase 2
Alternative Name
beta4Gal-T2
Location
1p34.1
Gene ID
8704
Summary
This galactosyltransferase is essential for building complex carbohydrate structures, transferring galactose to acceptor sugars and playing a vital role in various cellular processes.
For Research Use Only.
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