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GlycoErase™ DPY19L2 Knockout Human Bladder Cancer Cell 5637

CAT#: GLJF-0525-JF10

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Overview Specification Target Information Related Products
Overview
Description
Loss of DPY19L2 in human bladder bancer bell 5637, which normally expresses the dpy-19 like C-mannosyltransferase 2 primarily involved in spermatogenesis, might unveil unconventional roles for C-mannosylation within the context of bladder carcinoma, potentially influencing unique glycosylation pathways relevant to tumor biology.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:3~1:6
Cell Line
5637
Primary Disease
Bladder Urothelial Carcinoma
Lineage
Bladder/Urinary Tract
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
DPY19L2
Full Name
Dpy-19 like C-mannosyltransferase 2
Alternative Name
SPATA34, FLJ32949
Location
12q14.2
Gene ID
283417
Summary
Required for sperm head elongation and acrosome formation during spermatogenesis, essential for male fertility.
For Research Use Only.
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