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GlycoErase™ FUT10 Knockout Human Prostate Cancer Cell 22RV1

CAT#: GLJF-0525-JF273

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Overview Specification Target Information Related Products
Overview
Description
The FUT10 knockout 22RV1 cell line, lacking fucosyltransferase 10, offers a model to examine the consequences of disrupted N-glycan fucosylation in multiple cellular compartments within prostate cancer cells; the loss of FUT10 function, impacting the Golgi apparatus, endoplasmic reticulum, and nucleoplasm, may reveal critical roles of N-glycan fucosylation in prostate cancer biology.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epitheloid cells, adherent
Passage Ratio
1:3~1:10
Cell Line
22RV1
Primary Disease
Prostate Adenocarcinoma
Lineage
Prostate
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
FUT10
Full Name
Fucosyltransferase 10
Alternative Name
Alpha-1,3-fucosyltransferase, Fucosyltransferase FucT-III, FucT-III
Location
8p12
Gene ID
84750
Summary
Fucosyltransferase involved in N-glycan fucosylation; located in the Golgi apparatus, endoplasmic reticulum, and nucleoplasm.
For Research Use Only.
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