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GlycoErase™ FUT2 Knockout Human Prostate Cancer Cell 22RV1

CAT#: GLJF-0525-JF275

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Overview Specification Target Information Related Products
Overview
Description
The FUT2 knockout 22RV1 cell line, lacking fucosyltransferase 2, allows for the study of disrupted soluble ABO blood group antigen synthesis in prostate cancer; the loss of FUT2 function, one of the two enzymes responsible for the final step in this synthesis, may reveal the significance of these antigens in the context of prostate cancer development and interaction with the host environment.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epitheloid cells, adherent
Passage Ratio
1:3~1:10
Cell Line
22RV1
Primary Disease
Prostate Adenocarcinoma
Lineage
Prostate
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
FUT2
Full Name
Fucosyltransferase 2
Alternative Name
Se2, sej, SEC2, SE
Location
19q13.33
Gene ID
2524
Summary
Encodes one of two galactoside 2-L-fucosyltransferases; crucial for the final step in soluble ABO blood group antigen synthesis.
For Research Use Only.
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