GlycoErase™ FUT7 Knockout Human Prostate Cancer Cell 22RV1 (CAT#: GLJF-0525-JF280)

Description	The FUT7 knockout 22RV1 cell line, also involved in sialyl-Lewis X synthesis, similar to FUT6, allows for the study of sialyl-Lewis X's role in prostate cancer cell adhesion, metastasis, and E-selectin ligand presentation; comparing FUT6 and FUT7 knockout phenotypes may reveal redundant or distinct contributions of these fucosyltransferases in prostate cancer progression.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epitheloid cells, adherent
Passage Ratio	1:3~1:10
Cell Line	22RV1
Primary Disease	Prostate Adenocarcinoma
Lineage	Prostate

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	DMEM & FBS & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	FUT7
Full Name	Fucosyltransferase 7
Alternative Name	Alpha-1,3-fucosyltransferase 7, Fucosyltransferase FucT-VI, FucT-VI
Location	9q34.3
Gene ID	2529
Summary	Golgi membrane protein responsible for the creation of sialyl-Lewis X antigens, which play a role in leukocyte trafficking and inflammation.