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GlycoErase™ FUT9 Knockout IST-Mes1 Cell Line

CAT#: GLJF-0425-JF794

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Overview Specification Target Information Related Products
Overview
Description
The FUT9 knockout IST-Mes1 cell line lacks FUT9 protein, fucosyltransferase 9, involved in Lewis X (LeX) antigen synthesis. FUT9 knockout in IST-Mes1 cells can be used to study Lewis X antigen's role in Pleural Mesothelioma, potentially affecting cell adhesion, migration, and functions related to Lewis X antigen presentation in the tumor microenvironment.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:8
Cell Line
IST-Mes1
Primary Disease
Pleural mesothelioma
Lineage
Pleura
Lineage Subtype
Pleural mesothelioma
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Glutamine
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
FUT9
Full Name
Fucosyltransferase 9
Alternative Name
Fuc-TIX
Location
6q16.1
Gene ID
10690
Summary
Golgi-localized fucosyltransferase that catalyzes the final step in Lewis X (LeX) antigen biosynthesis; essential for organ development during embryogenesis.
For Research Use Only.
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