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GlycoErase™ HEK293F-ΔB3GNT4 Cell Line

CAT#: GLJF-0425-JF374

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Overview Specification Target Information Related Products
Overview
Description
This B3GNT4 knockout (HEK293F) cell line lacks the B3GNT4 protein, a UDP-GlcNAc:betaGal beta-1,3-O-acetylglucosaminyltransferase 4. This gene encodes a member of the beta-1,3-O-acetylglucosaminyltransferase protein family. The encoded enzyme is involved in the biosynthesis of poly-N-acetyllactosamine chains and prefers lacto-N-neotetraose as a substrate. Loss of B3GNT4 function may disrupt the biosynthesis of poly-N-acetyllactosamine chains.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293F
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
B3GNT4
Full Name
UDP-GlcNAc:BetaGal Beta-1,3-O-acetylglucosaminyltransferase 4
Alternative Name
B3GN-T4, beta3Gn-T4
Location
12q24.31
Gene ID
79369
Summary
Involved in the biosynthesis of poly-N-acetyllactosamine chains, utilizing lacto-N-neotetraose as a preferred substrate.
For Research Use Only.
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