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GlycoErase™ HEK293F-ΔGALNT7 Cell Line

CAT#: GLJF-0425-JF297

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Overview Specification Target Information Related Products
Overview
Description
This GALNT7 knockout (HEK293F) cell line lacks the GALNT7 protein, a polypeptide N-acetylgalactosaminyltransferase 7. This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine or threonine residues on target proteins. Loss of GALNT7 function may disrupt mucin-type O-linked glycosylation.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293F
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
GALNT7
Full Name
Polypeptide N-acetylgalactosaminyltransferase 7
Alternative Name
GalNAc-T7
Location
4q34.1
Gene ID
51809
Summary
Controls the initiation of mucin-type O-linked protein glycosylation by transferring N-acetylgalactosamine to serine and threonine residues; type II transmembrane protein.
For Research Use Only.
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