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| Size | Qty | Add To Basket |
|---|---|---|
| 2 M cells/vial*2 |
| Description | This GALNT9 knockout (HEK293F) cell line lacks the GALNT9 protein, a polypeptide N-acetylgalactosaminyltransferase 9. This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine or threonine residues on target proteins. Loss of GALNT9 function may disrupt mucin-type O-linked glycosylation. |
| Product Type | KO Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:2~1:4 |
| Cell Line | HEK293F |
| Lineage | Embryonic kidney |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | PCR, Sanger Sequencing |
| Culture Medium | DMEM |
| Application | Functional assay |
| Size | 2 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | GALNT9 |
| Full Name | Polypeptide N-acetylgalactosaminyltransferase 9 |
| Alternative Name | GalNAc-T9 |
| Location | 12q24.33 |
| Gene ID | 50614 |
| Summary | Essential for the synthesis of mucin-type O-glycans, transferring GalNAc to target proteins and contributing to diverse cellular functions, including cell signaling and adhesion. |