GlycoErase™ HEK293F-ΔMGAT3 Cell Line (CAT#: GLJF-0425-JF317)

Description	This MGAT3 knockout (HEK293F) cell line lacks the MGAT3 protein, a mannosyl (alpha-1,3-)-glycoprotein beta-1,4-O-acetylglucosaminyltransferase. This gene encodes a member of the MGAT family of enzymes. The encoded protein is a type II membrane protein involved in the conversion of high mannose to hybrid and complex N-glycans. Loss of MGAT3 function may disrupt N-glycan processing and affect glycoprotein function.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293F
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	DMEM
Application	Functional assay
Size	2 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	MGAT3
Full Name	Beta-1,4-mannosyl-glycoprotein 4-Beta-O-acetylglucosaminyltransferase
Alternative Name	GNT-III
Location	22q13.1
Gene ID	4248
Summary	Transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides, producing a bisecting GlcNAc.