GlycoErase™ HEK293T B4GALT1 Knockout Cell Line

We are pleased to present a B4GALT1 knockout HEK293T cell line for researchers studying the biosynthesis of various glycoconjugates. This cell line, lacking the B4GALT1-encoded beta-1,4-galactosyltransferase 1, serves as a model for investigating the consequences of disrupting this enzyme's activity. Utilizing HEK293T cells, a platform well-suited for gene function and regulation studies, researchers can explore the specific role of B4GALT1 in the biosynthesis of different glycoconjugates and saccharide structures, and its impact on cellular functions.

KO Cell Lines

Human

Epithelial-like, adherent

1:2~1:4

HEK293T

Embryonic kidney

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

DMEM & FBS & Penicillin/Streptomycin

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

B4GALT1

N-acetyl-D-glucosamine

Beta-1,4-galactosyltransferase 1

beta4Gal-T1, GGTB2

9p21.1

A key player in glycan assembly, this enzyme specifically adds galactose to various sugar molecules, contributing to the structural diversity of glycoconjugates.