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| Size | Qty | Add To Basket |
|---|---|---|
| 2 M cells/vial*2 |
| Description | To assess the functional significance of vesicle-associated GalNAc-transferases in O-linked glycosylation, we are pleased to work on creating an GALNT17 knockout HEK293T model. In these cells, the potential alterations in O-glycan processing, resulting from GALNT17 loss, can be meticulously studied, shedding light on its role in intracellular trafficking-related glycosylation. |
| Product Type | KO Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:2~1:4 |
| Cell Line | HEK293T |
| Lineage | Embryonic kidney |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | PCR, Sanger Sequencing |
| Culture Medium | DMEM & FBS & Penicillin/Streptomycin |
| Application | Functional assay |
| Size | 2 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | GALNT17 |
| Full Name | Polypeptide N-acetylgalactosaminyltransferase 17 |
| Alternative Name | GALNTL3, GalNAc-T19, GalNAc-T5L, WBSCR17, GalNAc-T17, ppGalNAc-T17 |
| Location | 7q11.22 |
| Gene ID | 64409 |
| Summary | Encodes an N-acetylgalactosaminyltransferase; located near the common deleted region in Williams-Beuren syndrome (WBS), a developmental disorder. |