GlycoErase™ ILKAP Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF412)

Description	GlycoErase™ ILKAP knockout HEK293 cell line is a human embryonic kidney (HEK293) model with ILKAP expression removed. ILKAP encodes a protein serine/threonine phosphatase that regulates integrin-linked kinase (ILK) and selectively modulates ILK-mediated signaling pathways, including glycogen synthase kinase 3β and WNT signaling. This knockout provides a platform for studying cell adhesion, phosphatase regulation, and integrin-mediated signaling in a human cellular context, supporting applications in cancer biology, cell signaling research, and therapeutic development.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	ILKAP
Full Name	Ilk Associated Serine/Threonine Phosphatase
Alternative Name	PP2CD; PPM1O; ILKAP2; ILKAP3; PP2C-DELTA
Location	2q37.3
Gene ID	80895
Summary	This gene encodes a PP2C family serine/threonine phosphatase that interacts with integrin-linked kinase (ILK), influencing ILK-mediated glycogen synthase kinase 3 beta regulation and participating in Wnt signaling.