GlycoErase™ MGAT4B Knockout Human Bladder Cancer Cell 5637 (CAT#: GLJF-0525-JF63)

Description	The MGAT4B knockout 5637 cell line, lacking mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 4B involved in complex N-glycan synthesis, enables the study of complex N-glycan disruption in bladder carcinoma, potentially affecting N-glycan processing and glycoprotein function in tumor-relevant pathways.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:3~1:6
Cell Line	5637
Primary Disease	Bladder Urothelial Carcinoma
Lineage	Bladder/Urinary Tract

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	MGAT4B
Full Name	Alpha-1,3-mannosyl-glycoprotein 4-Beta-O-acetylglucosaminyltransferase B
Alternative Name	GnT-Ivb
Location	5q35.3
Gene ID	11282
Summary	Regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus by catalyzing the transfer of GlcNAc in a beta-1,4 linkage.