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GlycoErase™ POFUT1 Knockout CHO-S Cell Line

CAT#: GLJF-0425-JF199

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Overview Specification Target Information Related Products
Overview
Description
To probe POFUT1 protein O-fucosyltransferase 1 function in CHO-S cells, and to determine its role in O-fucosylation of epidermal growth factor repeats, the POFUT1 knockout CHO-S cell line is utilized to investigate O-fucosylation disruption of EGF repeats and its potential effects on EGF repeat-containing protein functions in CHO-S cells.
Product Type
KO Cell Lines
Species
Hamster
Cell Morphology
Epithelial, suspension growth
Passage Ratio
1:3~1:5
Cell Line
CHO-S
Lineage
Chinese hamster ovary
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
CDMF & Glutamine & Penicillin/Streptomycin
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
POFUT1
Full Name
Protein O-fucosyltransferase 1
Alternative Name
O-FUT, KIAA0180, FUT12, O-Fuc-T
Location
20q11.21
Gene ID
23509
Summary
Adds O-fucose to serine or threonine residues in epidermal growth factor-like repeats of various proteins, influencing ligand-induced receptor signaling.
For Research Use Only.
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