GlycoErase™ ST6GALNAC6 Knockout CHO-K1 Cell Line (CAT#: GLJF-0425-JF99)

Description	The ST6GALNAC6 knockout CHO-K1 cell line, obtained through gene editing technology for ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6, preliminary experimental data indicates that this cell line may also significantly disrupt the normal cell-matrix interaction pattern of CHO cells, exhibiting similar cell phenotype characteristics to ST6GALNAC5 knockout cell line, both by deeply altering cell surface sialylation modification levels, thus significantly affecting the complex interaction patterns and dynamic processes of CHO cells with the extracellular matrix.
Product Type	KO Cell Lines
Species	Hamster
Cell Morphology	Epithelial, adherent
Passage Ratio	1:3~1:5
Cell Line	CHO-K1
Lineage	Chinese hamster ovary

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	2 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	ST6GALNAC6
Full Name	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Alternative Name	SIAT7F, ST6GALNACVI
Location	9q34.11
Gene ID	30815
Summary	Modifies proteins and ceramides on the cell surface by adding sialic acid, influencing cell-cell and cell-extracellular matrix interactions.