GlycoErase™ UGT8 Knockout CHO-S Cell Line (CAT#: GLJF-0425-JF234)

Description	To analyze UGT8 UDP-glycosyltransferase function in CHO-S cells, and to elucidate its role in galactocerebroside biosynthesis, crucial for myelin sheath formation, the UGT8 knockout CHO-S cell line provides a model to study galactocerebroside biosynthesis disruption and, while myelin-focused, potentially reveal novel roles for UGT8 or galactocerebrosides in broader CHO-S glycosylation pathways and cellular functions.
Product Type	KO Cell Lines
Species	Hamster
Cell Morphology	Epithelial, suspension growth
Passage Ratio	1:3~1:5
Cell Line	CHO-S
Lineage	Chinese hamster ovary

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	CDMF & Glutamine & Penicillin/Streptomycin
Application	Functional assay
Size	2 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	UGT8
Full Name	UDP glycosyltransferase 8
Alternative Name	CGT
Location	4q26
Gene ID	7368
Summary	Catalyzes the transfer of galactose to ceramide, a crucial step in the biosynthesis of galactocerebrosides, essential components of myelin.