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GlycoFlux™ AAV1-Human LDHAL6A Viral Particle (CAT#: GLJF-1025-JF954)

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SPECIFIC INQUIRY
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Description GlycoFlux™ AAV1-LDHAL6A Viral Particle drives LDHAL6A expression with predicted L-lactate dehydrogenase activity to refine control of lactate/pyruvate balance in specialized cells; this product demonstrates strong uptake in central nervous system and smooth muscle to enable extended physiology studies in a replication-defective, research-only format.
Product Type Recombinant AAV1
Target LDHAL6A
Species Human
Promotor CMV, CAG, TRE, or other promoters
Tissue Tropism Smooth muscle, Central Nervous System (CNS), Retina, Pancreas, Inner Ear, Heart, Liver
Packaging System AAV Triple-Plasmid Transfection System
Packaging Cell HEK293T
Application This AAV1 viral particle is primarily used for overexpressing target genes in muscle tissues (smooth muscle, heart) and the central nervous system (CNS) / sensory organs (retina, inner ear). It is an ideal tool for research and pre-clinical studies focused on myopathies, cardiac disorders, and certain neurological or sensory genetic diseases.
Shipping Shipped on dry ice, with temperature maintained at ≤ -80°C.
Storage Store at -80°C to preserve viral titer and stability.
Handling Notes Store this product at -80°C and minimize freeze-thaw cycles to preserve viral titer. For safety, handle in a certified biological safety cabinet and wear appropriate PPE (lab coat, gloves, and eye protection).
Product Disclaimer This product is intended for research use only and is not approved for diagnostic procedures or clinical applications. Users are solely responsible for implementing appropriate safety practices and complying with all applicable laws, regulations, and institutional policies. While Creative Biolabs is committed to rigorous quality control, no guarantee is made regarding performance in any particular assay or application.
Titer Assay qPCR/TCID50
Mycoplasma Test No mycoplasma contamination was detected.
Sterility Sterility testing verified the absence of microbial contamination.
Transduction Evaluation Upon request, Creative Biolabs performs in vitro or in vivo transduction assays to assess AAV delivery to target cells and to quantify transgene expression and function.
Insert Identity Confirmation All AAV preparations from Creative Biolabs are verified for vector-genome identity by PCR. In this assay, target cells are transduced with serial dilutions of the AAV preparation, harvested after a short incubation, and genomic DNA is isolated; a defined region of the packaged transgene is then PCR-amplified to confirm the expected sequence.
Full Name Lactate Dehydrogenase A Like 6A
Alternative Name LDH6A
Location 11p15.1
Gene ID 160287
Summary Enables L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process and pyruvate metabolic process. Located in cytoplasm.
For Research Use Only.
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